Techniques

Target controlled infusion anaesthesia in children

G Wilson
Southern African Journal of Anaesthesia and Analgesia | Vol 16, No 1 | a452 | DOI: https://doi.org/10.1080/22201173.2010.10872653 | © 2010 G Wilson | This work is licensed under CC Attribution 4.0
Submitted: 03 November 2025 | Published: 01 February 2010

About the author(s)

G Wilson,, South Africa

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Abstract

Total intravenous anaesthesia (TIVA) has grown rapidly in popularity over the last two decades in both adult and paediatric anaesthesia. This rapid increase in popularity is in part due to the widespread availability of drugs with favourable pharmacological properties and the development of new concepts in pharmacokinetic modelling, as well as advances in computer technology that have allowed the development of sophisticated anaesthetic delivery systems. This has led to refinements in blood plasma concentration targeting and dosing adjustments. A target controlled infusion (TCI) is an infusion controlled by a real time pharmacokinetic model that achieves a user defined blood or tissue concentration of a drug.

Keywords

target controlled infusion anaesthesia; children

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