Antiplatelet agents

Authors

Keywords:

antiplatelet agents, tissue injury, atherosclerotic thrombo-occlusive diseases

Abstract

Platelets play an important role in haemostasis after tissue injury. However, due to their inherent function, platelets are also involved in atherosclerotic thrombo-occlusive diseases of the cardiovascular and cerebrovascular systems.1,2 The formation of a thrombus is currently best explained by a cell-based model, comprising three processes of coagulation-initiation, amplification, and propagation.3

By studying platelets’ mechanisms of adhesion, activation, and amplification, the ability to develop treatment, management, and prevention of acute coronary syndromes, stent thrombosis, and stroke in individuals at risk, improves.4 Knowledge of antiplatelet drugs has substantial value in the perioperative setting.5

Author Biography

JA Dhulab, University of the Witwatersrand

Department of Anaesthesia, School of Clinical Medicine, Faculty of Health Sciences, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, South Africa

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Published

2023-11-24

Issue

FCA Refresher Course 2023

Section

FCA Refresher Course

License

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