Statistical issues in clinical research and linkage to other parts of the research process

Authors

Keywords:

statistical issues, clinical research

Abstract

Statistical issues in clinical research arise in many situations and at different stages of the research process. The purpose of this paper/opinion is to highlight the connections between different stages of a clinical research process with the statistical issues and how the challenges that may arise due to these issues may be mitigated. The paper also reflects on the ASA statement on misconceptions about p-values and how these can be addressed. The paper concludes by recommending that clinical researchers need some knowledge and understanding of basic statistical techniques. In addition, they would also benefit immensely from consulting with domain experts such as biostatisticians or statistical experts before embarking on their clinical research endeavours.

Author Biography

I Maposa, University of the Witwatersrand

Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, South Africa Health Science Research Office, Faculty of Health Sciences, University of the Witwatersrand, South Africa

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Published

2021-11-15

Issue

Section

FCA Refresher Course