Keywords:parathyroid disease, calcium, phosphate homeostasis
Parathyroid hormone (PH) is secreted in a calcium mediated feedback loop from the parathyroid glands and its primary function is calcium and phosphate homeostases. Four parathyroid glands are anatomically situated posterior to the thyroid, within the central compartment of the neck. PH is secreted in response to a low serum calcium level and it affects three major organs, namely bone, kidneys and proximal small intestines. This negative feedback loop between the parathyroid gland and these target organs in relation to altered levels of serum calcium concentration is described as the parathyroid axis.1,2
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