FCA 1 Anaesthetic Refresher Course

New drugs and anaesthesia

L. Thomo
Southern African Journal of Anaesthesia and Analgesia | Vol 28, No 5 | a1473 | DOI: https://doi.org/10.36303/SAJAA.2022.28.5.2891 | © 2022 L. Thomo | This work is licensed under Other
Submitted: 30 November 2025 | Published:

About the author(s)

L. Thomo, Department of Anaesthesia, School of Clinical Medicine, Faculty of Health Sciences, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, South Africa

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Abstract

The field of clinical anaesthesia has taken giant strides in terms of drug discovery and development. To date, the "ideal drug" does not exist—one with rapid onset of action, organ-independent metabolism, fast clearance, free from cardiorespiratory perturbations, minimal side effect profile. Recent drug innovations have focused primarily on matching previously unmet needs and identifying drawbacks of existing drugs and then altering their chemical structures to improve the safety and efficacy profile. There are currently numerous novel anaesthetic drugs at various stages of drug development.

Keywords

new drugs; anaesthesia; drug discovery; drug development

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