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FCA 1 Anaesthetic Refresher Course
An applied pharmacokinetic approach to adjusted drug dosing: Part II – pathophysiological states
Southern African Journal of Anaesthesia and Analgesia | Vol 29, No 6 | a1468 |
DOI: https://doi.org/10.36303/SAJAA.3066
| © 2023 S. Mahomed
| This work is licensed under Other
Submitted: 30 November 2025 | Published: 30 December 2023
Submitted: 30 November 2025 | Published: 30 December 2023
About the author(s)
S. Mahomed, Department of Anaesthesia, School of Clinical Medicine, Faculty of Health Sciences, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, South AfricaFull Text:
PDF (191KB)Abstract
In addition to age, gender, and pregnancy, pathophysiological states such as extremes of body weight, organ dysfunction, and critical illness with sepsis are factors that affect the pharmacokinetics of drugs, thereby necessitating an adjustment of drug dosing.1-5
Keywords
applied pharmacokinetics; adjusted drug dosing; pathophysiological states
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