Review Articles

A review of anti-obesity medications and anaesthesia

K.G. Gordon, G.A. Horsten, C.I. Botha
Southern African Journal of Anaesthesia and Analgesia | Vol 31, No 3 | a1261 | DOI: https://doi.org/10.36303/SAJAA.3208 | © 2025 K.G. Gordon, G.A. Horsten, C.I. Botha | This work is licensed under CC Attribution 4.0
Submitted: 20 November 2025 | Published: 30 June 2025

About the author(s)

K.G. Gordon, Department of Anaesthesia, University of KwaZulu-Natal, South Africa
G.A. Horsten, Private Practice, South Africa
C.I. Botha, Life Hilton Private Hospital, South Africa

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Abstract

The growing use of anti-obesity medications (AOM) in an expanding population of overweight and obese patients renders these drugs of importance to the anaesthesiologist. We review the current pharmacotherapy available in South Africa, the drugs' mechanism of action (MOA), and their potential interactions and implications with various anaesthetic agents during the perioperative period.

Keywords

anti-obesity medications; anaesthesia

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