The role of biomarkers and B-type natriuretic peptide in diagnosis and perioperative risk prediction

  • Nura Afshani University of Cape Town, Groote Schuur Hospital
  • Bruce M Biccard University of Kwazulu-Natal
  • Robert A Dyer University of Cape Town
Keywords: B-type natriuretic peptide, BNP, risk prediction, troponins

Abstract

Biomarkers are important in diagnosis, assessment of disease severity, risk stratification and therapeutic decision-making. Recent studies strongly suggest that there is a role for B-type natriuretic peptide (BtNP) as a powerful prognostic predictor in both the preoperative and postoperative setting. An understanding is required of the specific statistical methodology that is used to assess the value of biomarkers. The main aim of this paper was to discuss the current role that BtNP plays in perioperative risk prediction.

Author Biographies

Nura Afshani, University of Cape Town, Groote Schuur Hospital
MBChB, DA(SA), FCA(SA) Anaesthesiology Specialist Department of Anaesthesia University of Cape Town Groote Schuur Hospital
Bruce M Biccard, University of Kwazulu-Natal
MBChB, FFARCSI, FCA(SA), MMedSci, PhD Principal Specialist in Anaesthetics Department of Anaesthetics Nelson R Mandela School of Medicine University of KwaZulu-Natal
Robert A Dyer, University of Cape Town
PhD Professor Department of Anaesthesia University of Cape Town Groote Schuur Hospital
Published
2012-09-21
Section
Review Articles