Anaesthesia and Job syndrome

Authors

  • AT Bosenberg University of Cape Town

Abstract

Job's syndrome, an autosomal dominant disorder, was first described by Davis et al in 1966. He called the disorder 'Job syndrome' after the biblical figure Job: 'So went Satan forth from the presence of the Lord, and smote Job with sore boils from the sole of his foot unto his crown' (Job 2:7). Davis et al described two unrelated girls with lifelong histories of indolent Staphylococcal abscesses. Both had eczema soon after birth and had persistent weeping lesions on the ears and face. Both girls had red hair and were fair-skinned. The authors suggested a defect in local resistance to Staphylococcal infection.

Author Biography

AT Bosenberg, University of Cape Town

Department of Anaesthesia

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Syndromic vignettes in paediatric anaesthesia